For many years there has been a debate about the role of the parietal lobe in the generation of behavior. Does it generate movement plans (intention) or choose objects in the environment for further processing? To answer this, we focus on the lateral intraparietal area (LIP), an area that has been shown to play independent roles in target selection for saccades and the generation of visual attention. Based on results from a variety of tasks, we propose that LIP acts as (...) a priority map in which objects are represented by activity proportional to their behavioral priority. We present evidence to show that the priority map combines bottom-up inputs like a rapid visual response with an array of top-down signals like a saccade plan. The spatial location representing the peak of the map is used by the oculomotor system to target saccades and by the visual system to guide visual attention. (shrink)

The posterior parietal cortex and frontal eye field contain maps of visual salience on which the decision to choose a saccade may be based. However, an averaging express saccade is not represented by a victorious unimodal representation in the superior colliculus. Normalization as described by Findlay & Walker is not necessary for the generation of saccades.

This volume is a collection of essays by various contributors in honor of the late Laurence Berns, Richard Hammond Elliot Tutor Emeritus at St. John's College, Annapolis. The essays address the literary, political, theological, and philosophical themes of his life's work as a scholar, teacher, and constant companion of the "great books.".

Ontology is one strategy for promoting interoperability of heterogeneous data through consistent tagging. An ontology is a controlled structured vocabulary consisting of general terms (such as “cell” or “image” or “tissue” or “microscope”) that form the basis for such tagging. These terms are designed to represent the types of entities in the domain of reality that the ontology has been devised to capture; the terms are provided with logical defi nitions thereby also supporting reasoning over the tagged data. Aim: This (...) paper provides a survey of the biomedical imaging ontologies that have been developed thus far. It outlines the challenges, particularly faced by ontologies in the fields of histopathological imaging and image analysis, and suggests a strategy for addressing these challenges in the example domain of quantitative histopathology imaging. The ultimate goal is to support the multiscale understanding of disease that comes from using interoperable ontologies to integrate imaging data with clinical and genomics data. (shrink)

Commentary on Angelo E. Volandes & Michael K. Paasche-Orlow, Health Literacy, Health Inequality and a Just Healthcare System.

Radical ecology typically brings to mind media images of ecological activists standing before loggers' saws, staging anti-nuclear marches, and confronting polluters on the high seas. Yet for more than twenty years, the activities of organizations such as the Greens and Earth First! have been influenced by a diverse, less-publicized group of radical ecological philosophers. It is their work—the philosophical underpinnings of the radical ecological movement—that is the subject of _Contesting Earth's Future_. The book offers a much-needed, balanced appraisal of radical (...) ecology's principles, goals, and limitations. Michael Zimmerman critically examines the movement's three major branches—deep ecology, social ecology, and ecofeminism. He also situates radical ecology within the complex cultural and political terrain of the late twentieth century, showing its relation to Martin Heidegger's anti-technological thought, 1960s counterculturalism, and contemporary theories of poststructuralism and postmodernity. An early and influential ecological thinker, Zimmerman is uniquely qualified to provide a broad overview of radical environmentalism and delineate its various schools of thought. He clearly describes their defining arguments and internecine disputes, among them the charge that deep ecology is an anti-modern, proto-fascist ideology. Reflecting both the movement's promise and its dangers, this book is essential reading for all those concerned with the worldwide ecological crisis. (shrink)

Substance addiction affects millions of individuals worldwide and yet there is no consensus regarding its conceptualisation. Recent neuroscientific developments fuel the view that addiction can be classified as a brain disease, whereas a different body of scholars disagrees by claiming that addictive behaviour is a choice. These two models, the Brain Disease Model and the Choice Model, seem to oppose each other directly. This article contends the belief that the two models in the addiction debate are polar opposites. It shows (...) that it is not the large amount of addiction research in itself what sets the models apart, but rather their extrapolated conclusions. Moreover, some of the most fiercely debated aspects - for instance, whether or not addiction should be classified as a disease or disorder - are irrelevant for the conceptualisation of addiction. Instead, the real disagreement is shown to revolve around capacities. Discussing addiction-related capacities, especially regarding impaired control, rather than the assumed juxtaposition of the two models can be considered the true addiction debate. More insight into the extent to which the capacities of the addicted individual were affected would be highly useful in various other areas, especially legal responsibility. (shrink)

In autonomous action the agent herself directs and governs the action. But what is it for the agent herself to direct and to govern? One theme in a series of articles by Harry G. Frankfurt is that we can make progress in answering this question by appeal to higher-order conative attitudes. Frankfurt's original version of this idea is that in acting of one's own free will, one is not acting simply because one desires so to act. Rather, it is also (...) true that this desire motivates one's action because one desires that this desire motivate one's action. This latter desire about the motivational role of one's desire is a second-order desire. It is, in particular, what Frankfurt calls a second-order “volition.” And, according to Frankfurt's original proposal, acting of one's own free will involves in this way such second-order, and sometimes yet higher order, volitions. (shrink)

Cases of modest sociality are cases of small scale shared intentional agency in the absence of asymmetric authority relations. I seek a conceptual framework that adequately supports our theorizing about such modest sociality. I want to understand what in the world constitutes such modest sociality. I seek an understanding of the kinds of normativity that are central to modest sociality. And throughout we need to keep track of the relations—conceptual, metaphysical, normative—between individual agency and modest sociality. In pursuit of these (...) theoretical aims, I propose that a central phenomenon is shared intention. I argue that an adequate understanding of the distinctiveness of the intentions of individuals allows us to provide a construction of attitudes of the participants, and of relevant inter-relations and contexts that constitutes shared intention. I explain how shared intention, so understood, differs from a simple equilibrium within common knowledge. And I briefly contrast my views with aspects of views of John Searle and Margaret Gilbert. (shrink)

Drawing upon selected literature from the United Kingdom, Denmark, and Canada we examine how Foucault's concepts of ‘episteme’, ‘rupture’ ‘parrhesia’ ‘care of the self’, and ‘problemitization’ have been applied to particular contexts of leadership development, pedagogy, nursing knowledge, and the relationship between caring and politics. Our aims are threefold: to give examples of how selected Foucauldian concepts have been taken up in practice; to clarify how we are positioned today as nurses; and to invite more nurses to engage critically with (...) historical inquiry and to engage in deep philosophical reflection about their relationship with nursing. We begin by examining the conditions and circumstances of Foucault's life, and conclude by posing the question in our subtitle to stimulate debate about the philosophical relevance of Foucauldian scholarship to nursing. (shrink)

I argue that the many worlds explanation of quantum computation is not licensed by, and in fact is conceptually inferior to, the many worlds interpretation of quantum mechanics from which it is derived. I argue that the many worlds explanation of quantum computation is incompatible with the recently developed cluster state model of quantum computation. Based on these considerations I conclude that we should reject the many worlds explanation of quantum computation.

This is a reply to discussions by David Copp, Tamar Schapiro, and Sergio Tenenbaum of Michael E. Bratman, Shared Agency: A Planning Theory of Acting Together.

Physical theories often characterize their observables with real number precision. Many non-fundamental theories do so needlessly: they are more precise than they need to be to capture the physical matters of fact about their observables. A natural expectation is that a truly fundamental theory will require its full precision in order to exhaustively capture all of the fundamental physical matters of fact. I argue against this expectation and I show that we do not have good reason to expect that the (...) standard of precision set by successful theories, or even by a truly fundamental theory, will match the granularity of the physical facts. (shrink)

Controversy and activism have long been linked to the subject of primate research. Even in the midst of raging ethical debates surrounding fertility treatments, genetically modified foods and stem-cell research, there has been no reduction in the campaigns of activists worldwide. Plying their trade of intimidation aimed at ending biomedical experimentation in all animals, they have succeeded in creating an environment where research institutions, often painted as guilty until proven innocent, have avoided addressing the issue for fear of becoming targets. (...) One area of intense debate is the use of primates in stroke research. Despite the fact that stroke kills more people each year than AIDS and malaria, and less than 5% of patients are candidates for current therapies, there is significant opposition to primate stroke research. A balanced examination of the ethics of primate stroke research is thus of broad interest to all areas of biomedical research. (shrink)

The Strange Situation procedure was developed by Ainsworth two decades agoas a means of assessing the security of infant-parent attachment. Users of the procedureclaim that it provides a way of determining whether the infant has developed species-appropriate adaptive behavior as a result of rearing in an evolutionary appropriate context, characterized by a sensitively responsive parent. Only when the parent behaves in the sensitive, species-appropriate fashion is the baby said to behave in the adaptive or secure fashion. Furthermore, when infants are (...) observed repeatedly in the Strange Situation,the pattern of behavior is said to be highly similar, and this pattern is said to predict the infants' future behavior in a diverse array of contexts. After an exhaustive review of the literature, it is shown that these popular claims are empirically unsupported in their strong form, and that the interpretations in terms of biological adaptationare misguided. There is little reliable evidence about the specific dimensions of parental behavior that affect Strange Situation behavior, although there does appear to be some relationship between these constructs. Temporal stability in security of attachment ishigh only when there is stability in family and caretaking circumstances. Likewise, patterns of Strange Situation behavior only have substantial predictive validity in similarly stable families. Implications for future research and theorizing — particularly as they relate to the use of evolutionary biology in psychological theory — are discussed. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:78 Discussion c:\users\kenneth\documents\type3401\rj 3401 193 red.docx 2014-05-14 8:54 PM MORE WIT IN PM Michael E. Berumen 37155 Dickerson Run Windsor, co 80550, usa [email protected] eldom does one find a piece by Bertrand Russell without a morsel of humour or wryness. Sometimes the Russellian wit is obvious. Other times it is more subtle, maybe even requiring a second look just to be sure. Headlong into some of his most (...) technical and difficult works, a delightful bon mot might suddenly punctuate the philosophical solemnity. One doesn’t ordinarily think of Principia Mathematica as a sourcebook for Russellian waggishness, but it is there, to be sure—albeit one will negotiate many pages of symbols and scant prose before finding a specimen. Perhaps the best-known witticism amongst cognoscenti is, after having proved 1 + 1 = 2 (PM ∗110.643, 2: 83), the authors observe, “The above proposition is occasionally useful.” The most complete directory for these jewels that I know is by Kenneth Blackwell.1 I thought it unlikely another would be found, so imagine my surprise when, after having dusted off my seldom-used Volume 3 to look something up, I came across a droll nugget that (to the best of my knowledge) has not been highlighted before. Something tells me Russell was biting down on his pipe stem and had a twinkle in his eye when he (I assume Russell, but they, anyway) wrote in the summary of Section A of Part vi, “Quantity”: Great difficulties are caused, in this section, by the existence-theorems and the question of types. These difficulties disappear if the axiom of infinity is assumed, but it seems improper to make the theory of (say) 2/3 depend upon the assumption that the number of objects in the universe is not finite. (PM 3: 234; italics mine) “Improper” indeed, the erstwhile Victorian says! By way of explanation, he goes on to say, We have, accordingly, taken pains not to make this assumption, except where, as in the theory of real numbers, it is really essential, and not merely convenient. Even that has a bit of Russellian sarcasm. So, accept the challenge and find another. In the meantime, take comfort in the knowledge that the sometimes controversial Axiom of Infinity is an unnecessary assumption in mixing one part soda and two parts Red Hackle. 1 “The Wit and Humour of Principia Mathematica”, Russell 31 (2011): 151–60. S... (shrink)

Ray Kurzweil and others have posited that the confluence of nanotechnology, artificial intelligence, robotics, and genetic engineering will soon produce posthuman beings that will far surpass us in power and intelligence. Just as black holes constitute a ldquo;singularityrdquo; from which no information can escape, posthumans will constitute a ldquo;singularity:rdquo; whose aims and capacities lie beyond our ken. I argue that technological posthumanists, whether wittingly or unwittingly, draw upon the long-standing Christian discourse of ldquo;theosis,rdquo; according to which humans are capable of (...) being God or god-like. From St. Paul and Luther to Hegel and Kurzweil, the idea of human self-deification plays a prominent role. Hegel in particular emphasizes that God becomes wholly actualized only in the process by which humanity achieves absolute consciousness. Kurzweil agrees that God becomes fully actual only through historical processes that illuminate and thus transform the entire universe. The difference is that for Kurzweil and many other posthumanists, our offspringmdash;the posthumansmdash;will carry out this extraordinary process. What will happen to Home sapiens in the meantime is a daunting question. (shrink)

Daniel, Michael E Review of: Martin Griver unearthed, by Odhran O'Brien, Strathfield, NSW: St Pauls, 2014, pp. 261, hardback, $39.95; paperback, $35.95.

A study of Chrisoula Andreou’s Choosing Well. Andreou defends “a revisionary way of understanding instrumental rationality,” one that contrasts with “standard conceptions of instrumental rationality” that are characteristic of orthodox decision theory. I applaud Andreou’s revisionary efforts but explore whether they lead to a yet further revision that appeals to norms of plan rationality.

Daniel, Michael E Review(s) of: Benedict XVI: A guide for the perplexed, by Tracey Rowland, London: T and T Clark International, 2010, pp.160, $29.95.

J. Baird Callicott seeks to resolve the problem of the intrinsic value of nature by utilizing a nondualistic paradigm derived from quantum theory. His approach is twofold. According to his less radical approach, quantum theory shows that properties once considered to be “primary” and “objective” are in fact the products of interactions between observer and observed. Values are also the products of such interactions. According to his more radical approach, quantum theory’s doctrine of internal relations is the model for the (...) idea that everything is intrinsically valuable because the “I” is intrinsically valuable and related to everything else. I argue that humanity’s treatment of nature will become respectful only as humanity’s awareness evolves toward nondualism, and that such nondualistic awareness will not be produced by changes in scientific theory alone. Nevertheless, as Callicott suggests, such changes may be harbingers of evolutionary trends in human awareness. I conclude with a sketch of how nondualism, especially in its panentheistic version, provides the basis for environmental ethics. (shrink)